Cancer signature ensemble integrating cfDNA methylation, copy number, and fragmentation facilitates multi-cancer early detection

Personalised circulating tumour DNA assay with large-scale mutation coverage for sensitive minimal residual disease detection in colorectal cancer

Dynamic changes in longitudinal circulating tumour DNA profile during metastatic colorectal cancer treatment?

EBS-seq: enrichment-based method for accurate analysis of 5-hydroxymethylcytosine at single-base resolution

Mutational evolution after chemotherapy-progression in metastatic colorectal cancer revealed by circulating tumor DNA analysis

Circulating Tumor DNA Dynamics and Treatment Outcome of Regorafenib in Metastatic Colorectal Cancer?

Efficacy of Olaparib in Treatment-Refractory, Metastatic Breast Cancer with Uncommon Somatic BRCA Mutations Detected in Circulating Tumor DNA?

 Spatial and clonality-resolved 3D cancer genome alterations reveal enhancer-hijacking as a potential prognostic marker for colorectal cancer?

EMT-mediated regulation of CXCL1/5 for resistance to anti-EGFR therapy in colorectal cancer

Park YL, Kim HP, Ock CY, Min DW, Kang JK, Lim YJ, Song SH, Han SW, Kim TY.

Oncogene. 2022 Feb 16. doi: 10.1038/s41388-021-01920-4. Online ahead of print.

PMID: 35173310

Patient-derived organoids as a preclinical platform for precision medicine in colorectal cancer. 

Cho YW, Min DW, Kim HP, An Y, Kim S, Youk J, Chun J, Im JP, Song SH, Ju YS, Han SW, Park KJ, Kim TY. 

Mol Oncol. 2021 Nov 30. Online ahead of print.

Direct Detection of Low Abundance Genes of Single Point Mutation. 

Mishra S, Jeon J, Kang JK, Song SH, Kim TY, Ban C, Choi H, Kim Y, Kim M, Park JW. 

Nano Lett. 2021 Nov 10;21(21):9061-9068.

Lim Y, Kim S, Kang JK, Kim HP, Jang H, Han H, Kim H, Kim MJ, Lee KH, Ryoo SB, Park JW, Jeong SY, Park KJ, Kang GH, Han SW, Kim TY. 

Circulating tumor DNA sequencing in colorectal cancer patients treated with first-line chemotherapy with anti-EGFR. 

Sci Rep. 2021 Aug 11;11(1):16333.

Min DW, Kim HP, Kim J, Wen X, Kim S, Cho YW, Lim Y, Song SH, Han SW, Kwon S, Kang GH, Kim TY.

Phenotype-based single cell sequencing identifies diverse genetic subclones in CD133 positive cancer stem cells. 

Biochem Biophys Res Commun. 2021 Jun 18;558:209-215.

Kang JK, Heo S, Kim HP, Song SH,Yun H, Han SW, Kang GH, Bang D, Kim TY.

Liquid biopsy-based tumor profiling for metastatic colorectal cancer patients with ultra-deep targeted sequencing.

PLoS One. 2020 May 7;15(5):e0232754.doi: 10.1371/journal.pone.0232754.? 

Jang JE, Kim HP, Han SW, Jang H, Lee SH, Song SH, Bang D, KimTY. 

NFATC3- PLA2G15 FsuionTranscripts Identified by RNA sequencing promotes Tumor invasion and Proliferation in Colorectal Cancer Cell Lines. 

Cancer Res Treat. 2018 Jun 14. doi: 10.4143/crt.2018.103.

Cha Y, Kim HP, Lim Y, Han SW, Song SH, Kim TY. 

FGFR2 amplification ispredictive of sensitivity to regorafenib in gastric and colorectal cancersin vitro.

Mol Oncol 2018 Jun;12(7):993-1003. doi:10.1002/1878-0261.12194. 

Park YL,  Kim HP, Cho YW, Min DW, Cheon SK, Lim YJ, Song SH, Jin Kim S, Han SW, Park KJ, Kim TY

Activation of WNT/β-catenin signaling results in resistance to a dual PI3K/mTOR inhibitor in colorectal cancer cells harboring PIK3CA mutations.

Int J Cancer. 2018 Jul 6. doi: 10.1002/ijc.31662. 

Cheon SK, Kim HP, Park YL, Jang JE, Lim Y, Song SH, Han SW, Kim TY. 

Macrophage migration inhibitory factor promotes resistance to MEK blockade in KRAS mutant 

colorectal cancer cells. Mol Oncol. 2018 Aug;12(8):1398-1409

Song SH, Jeon MS, Nam JW, Kang JK, Lee YJ, Kang JY, Kim HP, Kang GH and Kim TY

Aberrant GATA2 epigenetic dysregulation induces a GATA2/GATA6 switch in human 

gastric cancer

Oncogene (2018) 37, 993-1004; doi:10.1038/onc.2017.397